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PRDX2 Polyclonal Antibody, Invitrogen™
Goat Polyclonal Antibody
Brand: Invitrogen PA518533
Additional Details : Weight : 0.01000kg
Description
This antibody is predicted to react with rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.
Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, particularly amino-terminal region containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20 - 30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.Specifications
PRDX2 | |
Polyclonal | |
Unconjugated | |
PRDX2 | |
AL022839; Band-8; Calpromotin; epididymis secretory sperm binding protein Li 2a; HEL-S-2a; HGNC:9353; MGC4104; Natural killer cell-enhancing factor B; NkefB; NKEF-B; peroxiredoxin 2; peroxiredoxin-2; Prdx2; protector protein; PRP; Prx II-1; PRX2; PRXII; PTX1; Tdpx1; TDX1; thiol specific antioxidant protein; thiol-specific antioxidant 1; thiol-specific antioxidant protein; thioredoxin dependent peroxide reductase 1; thioredoxin peroxidase 1; thioredoxin reductase; thioredoxin-dependent peroxide reductase 1; Torin; TPx; TPX1; TPx-B; TR; Trx dependent peroxide reductase 1; TSA | |
Goat | |
Antigen affinity chromatography | |
RUO | |
7001 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |
Western Blot | |
0.5 mg/mL | |
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
P32119 | |
PRDX2 | |
Synthetic peptide sequence (NVDDSKEYFSKHN) corresponding to the C-terminus amino acids of PRDX2 | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG |