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Invitrogen™ Precerebellin Polyclonal Antibody
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Product Code. 12838322
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Quantity:
100 μg
Unit Size:
100µg
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12838322 100 μg 100µg
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Product Code. 12838322 Supplier Invitrogen™ Supplier No. PA520159

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Description

Rabbit Polyclonal Antibody

A suggested positive control is 293 cell lysate. PA5-20159 can be used with blocking peptide PEP-0278.

Precerebellin is the precursor of the brain-specific hexadecapeptide cerebellin, a protein with substantial similarity to the globular region of the B chain of complement component C1q. Cerebellin exerts neuromodulatory functions by directly stimulating norepinephrine release via the adenylate cyclase/pka- dependent signaling pathway; and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release. The active form of precerebellin is highly enriched in postsynaptic structures of cerebellar Purkinje cells in cartwheel neurons of the dorsal cochlear nucleus. Because precerebellin belongs to the C1q/tumor necrosis factor superfamily of secreted proteins and has similarity to adiponectin and CTRP3, it has been suggested that precerebellin posseses functions other than those already stated.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Precerebellin
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene CBLN1
Gene Accession No. P23435, P63182, Q9R171
Gene Alias [des-Ser1]CER; [des-Ser1]-cerebellin; AI323299; Brain protein D3; Cbln1; CER; Cerebellin; cerebellin 1 precursor; cerebellin 1 precursor protein; cerebellin-1; des-Ser(1)-cerebellin; des-Ser1-cerebellin; Precerebellin
Gene Symbols CBLN1
Host Species Rabbit
Immunogen A 16 amino acid synthetic peptide from near the carboxy-terminus human precerebellin.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12404, 498922, 869
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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