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PTPN11 Monoclonal Antibody (OTI3F2), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Brand:  Origene Technologies TA501758

Encompass_Preferred

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Product Code. 17525101

  • 540.87€ / 100µL

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Description

Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noo syndrome as well as acute myeloid leukemia.
Specifications

Specifications

PTPN11
Monoclonal
0.99 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q06124
PTPN11
Full length human recombit protein of human PTPN11 produced in HEK293T cell.
100 μL
Primary
Canine, Human
Antibody
IgG2a
Flow Cytometry, Western Blot
OTI3F2
Unconjugated
PTPN11
BPTP3, CFC, JMML, METCDS, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2
Mouse
Affinity Chromatography
RUO
477488, 5781
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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