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PUF60 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10810-1-AP-20UL

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Product Code. 16837443

  • 145.00€ / 20µL

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Description

Description

PUF60 encodes a protein that is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.
Specifications

Specifications

PUF60
Polyclonal
Unconjugated
PUF60
FBP interacting repressor, FIR, PUF60, Ro binding protein 1, RoBP1, RoBPI, Siah binding protein 1, Siah BP1, SIAHBP1
Rabbit
Antigen Affinity Chromatography
RUO
22827, 67959, 84401
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.6 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q3UEB3, Q9UHX1, Q9WV25
Puf60
PUF60 Fusion Protein Ag1053
20 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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