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Tocris Bioscience™ Pyrimethamine
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Product Code. 18752774
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50 mg
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50mg
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Product Code. 18752774 Supplier Tocris Bioscience™ Supplier No. 3918/50

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68.80 EUR valid until 2026-03-31
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Description

Potent inhibitor of multidrug and toxin extrusion (MATE) transporters; also DHFR and STAT3 inhibitor

Potent inhibitor of multidrug and toxin extrusion (MATE) transporters (Ki values are 46 and 77 nM for human MATE2-K-HEK293 and MATE1-HEK293 cells respectively). Also inhibits dihydrofolate reductase (DHFR) and STAT3. Decreases proliferation of human autosomal dominant polycystic kidney disease cells.
TRUSTED_SUSTAINABILITY

Specifications

CAS 58-14-0
Quantity 50 mg
Molecular Formula C12H13ClN4
Formula Weight 248.71
Purity >99%
Molecular Weight (g/mol) 248.71
Chemical Name or Material Pyrimethamine
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