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  5. STEMCELL Technologies Quercetin (Hydrate)

STEMCELL Technologies Quercetin (Hydrate)

Product Code. 17180292
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10 g
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Product Code. 17180292 Supplier STEMCELL Technologies Supplier No. 73934

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Description

mTOR, PI3K/AKT, NF-kB, and tyrosine kinase pathway inhibitor; Inhibits PI3K and SRC kinases

  • Quercetin inhibits phosphoinositide 3-kinase isoforms (beta: IC50 = 5.4 μM; gamma: IC50 = 2.4 μM; delta: IC50 = 3.0 μM) and SRC kinases but only shows slight inhibitory activity against serine/threonine kinases ERK1/2 and p38 alpha, as well as protein kinase C (Navarro-Nunez et al.)
  • Stimulates glycolytic metabolism and promotes reprogramming of somatic cells (Zhang et al.)
  • Enhances reprogramming of human primary somatic cells to induced pluripotent stem cells (Zhu et al.)
  • Induces hypoxia-inducible factor-1α (HIF-1α) and inhibits cell proliferation (Triantafyllou et al.)
  • Promotes apoptosis of glioblastoma cells when used together with temozolomide (Sang et al.)
  • Reduces tumorigenicity of pancreatic cancer cells (Fan et al.)

Specifications

CAS 849061-97-8
Quantity 10 g
Molecular Formula C15H10O7 · XH2O
Purity ≥95%
Produkttitel
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