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RAB43 Mouse anti-Human, Clone: 3B2A8, Proteintech

Mouse Monoclonal Antibody

145.00€ - 410.00€

Specifications

Antigen RAB43
Clone 3B2A8
Concentration 1 mg/mL
Applications Western Blot
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16848735
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Proteintech
66654-1-IG-20UL
20 μL
145.00€
20µL
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16838735
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Proteintech
66654-1-IG-150UL
150 μL
410.00€
150µL
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Description

Description

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.
Specifications

Specifications

RAB43
1 mg/mL
Monoclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
ISY1, RAB11B, RAB41, RAB43, Ras related protein Rab 41, Ras related protein Rab 43
RAB43
IgG1
Protein G
Antibody
3B2A8
Western Blot
Unconjugated
Mouse
Human
Q86YS6
339122
RAB43 Fusion Protein Ag26911
Primary
-20°C
RAB43
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