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Invitrogen™ RAB5 Recombinant Rabbit Monoclonal Antibody (0K5J1)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA535161
This item is not returnable.
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Description
Immunogen sequence: KELQRQASPN IVIALSGNKA DLANKRAVDF QEAQSYADDN SLLFMETSAK TSMNVNEIFM AIAKKLPKNE PQNPGANSAR GRGVDLTEPT QPTRNQCCSN.
RAB5 are among the small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension. Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan. Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3.
Specifications
| RAB5 | |
| Recombinant Monoclonal | |
| 0.71 mg/mL | |
| PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| M0RC99, P20339, Q9CQD1 | |
| RAB5A | |
| A synthetic peptide corresponding to a sequence within amino acids 116-215 of human RAB5AA (P20339). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| ELISA, Western Blot | |
| 0K5J1 | |
| Unconjugated | |
| RAB5A | |
| 2410015H04Rik; AI663973; AU021172; nnyRab5a; Rab 5; Rab 5A; RAB5; RAB5A; RAB5A, member RAS oncogene family; Ras related protein; RAS-associated protein RAB5A; ras-related protein Rab-5A; Small GTP-binding protein rab5 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 271457, 5868, 64633 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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