Invitrogen™ RAE1 alpha/beta/delta/epsilon Monoclonal Antibody (199205)

Description

Reconstitute at 0.5 mg/mL in sterile PBS.

RAE1 (RNA Export 1) is a gene that plays a pivotal role in the nuclear export of mRNA in eukaryotic cells. This gene encodes a protein that is integral to the mRNA export machinery, ensuring the proper transport of mRNA from the nucleus to the cytoplasm for translation. The gene has several isoforms, including RAE1 alpha, beta, delta, and epsilon, which may have unique or overlapping functions in different tissues or developmental stages. The proper functioning of RAE1 and its isoforms is crucial for maintaining normal cellular processes and gene expression. Disruptions or mutations in the RAE1 gene can lead to significant defects in mRNA export, potentially causing a range of diseases, including neurodevelopmental disorders and cancers. Ongoing research into RAE1 and its various isoforms is essential for a deeper understanding of mRNA transport mechanisms and their broader implications in cellular health and disease.