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RASGAP Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00€ - 410.00€

Specifications

Antigen RASGAP
Concentration 0.19 mg/mL
Applications Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16810904
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Proteintech
12935-1-AP-20UL
20 μL
145.00€
20µL
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16800904
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Proteintech
12935-1-AP-150UL
150 μL
410.00€
150µL
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Description

Description

TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.
Specifications

Specifications

RASGAP
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
Unconjugated
Rabbit
Mouse, Human, Rat
P20936, P50904
218397, 25676, 5921
RASGAP Fusion Protein Ag3906
Primary
-20°C
RASA1
0.19 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
CM AVM, CMAVM, GAP, GTPase activating protein, p120GAP, p120RASGAP, PKWS, Ras p21 protein activator, RASA, RASA1, RASGAP
RASA1
IgG
Antigen Affinity Chromatography
Antibody
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SDS
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Documents

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