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R&D Systems™ Recombinant Human GDNF GMP Protein, CF

Artikelnummer. 31794279
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Quantity:
50 μg
Packungsgröße:
50µg
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31794279 50 μg 50µg
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Artikelnummer. 31794279 Lieferant R&D Systems™ Lieferanten-Nr. BTGDNFGMP050
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Estimated Shipment: 19-10-2026
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Beschreibung

Recombinant Protein

Measured in a cell proliferation assay using SH-SY5Y human neuroblastoma cells. The ED50 for this effect is 0.750-9.00 ng/mL in the presence of Recombinant Human GFR alpha -1/GDNF R alpha 1 Fc Chimera (Catalog # 714-GR ). The specific activity of recombinant human GDNF is >5.0 x 105 units/mg, which is calibrated against the human GDNF Reference Standard (NIBSC code: 09/266).
TRUSTED_SUSTAINABILITY

Spezifikation

Accession Number NP_000505.1
For Use With (Application) Bioactivity
Formulation Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Gene ID (Entrez) 2668
Molecular Weight (g/mol) MolecularWeight-observed: 8 kDa, under reducing conditions., MolecularWeight-theroretical: 11.3 kDa
Quantity 50 μg
Source E. coli-derived human GDNF protein Gly113 - Ile211 with & without an N-terminal Met Produced using non-animal reagents in an animal-free laboratory. Manufactured and tested under cGMP guidelines.
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. A minimum of 12 months when stored at ≤ -20 °C as supplied. Refer to lot specific COA for the Use by Date. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, ≤ -20 °C under sterile conditions after reconstitution.
Endotoxin Concentration <0.10 EU per 1 μg of the protein by the LAL method.
Gene Alias Astrocyte-derived trophic factor, ATF, ATF1, ATF2, glial cell derived neurotrophic factor, glial cell line derived neurotrophic factor, glial cell line-derived neurotrophic factor, HFB1-GDNF, HGDNF, HSCR3
Conjugate Unconjugated
Reconstitution Reconstitute at 500 μg/mL in sterile water.
Product Line R&D Systems
Purity or Quality Grade >97%, by SDS-PAGE with quantitative densitometry by Coomassie™ Blue Staining. The molecular weight by mass spectrometry is 22225 Da ± 5 Da, N-terminal Met species are also present (22356 ± 5 Da)
Protein GDNF
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