missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ SART1 Monoclonal Antibody (865709)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA561896
This item is not returnable.
View return policy
Description
Reconstitute with sterile PBS to a final concentration of 0.5 mg/mL.
This gene encodes two proteins, the SART1protein expressed in the nucleus of the majority of proliferating cells, and the SART1protein expressed in the cytosol of epithelial cancers. The SART1protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.
Specifications
| SART1 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| O43290 | |
| SART1 | |
| E. coli-derived recombinant human SART1, Asn647-Lys800. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Western Blot, Immunocytochemistry | |
| 865709 | |
| Unconjugated | |
| SART1 | |
| Ara1; Haf; Hom s 1; HOMS1; hSART-1; hSnu66; Hypoxia-associated factor; IgE autoantigen; MGC2038; mSART-1; rSART-1; Sart1; SART-1; SART1(259) protein; SART1(800) protein; SART1259; small nuclear ribonucleoprotein 110kDa (U4/U6.U5); SNRNP110; Snu66; SNU66 homolog; squamous cell carcinoma antigen recognised by T cells; squamous cell carcinoma antigen recognized by T cells; squamous cell carcinoma antigen recognized by T cells 1; squamous cell carcinoma antigen recognized by T-cells 1; U4/U6.U5 tri-snRNP-associated 110 kDa protein; U4/U6.U5 tri-snRNP-associated protein 1; U5-110K | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 9092 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction