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SEPT2 Mouse anti-Human, Mouse, Rat, Clone: 2F3B2, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 60075-1-IG-20UL
This item is not returnable.
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Description
Septin 2 is a filament-forming cytoskeletal GTPase. Septin 2 is required for normal organization of the actin cytoskeleton and plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. It is required for the progression through mitosis, and it forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, Septin 2 may be required for chromosome segregation and spindle elongation. Septin 2 also plays a role in ciliogenesis and collective cell movements.Specifications
| SEPT2 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| P42208, Q15019, Q91Y81 | |
| SEPT2 | |
| SEPT2 Fusion Protein Ag1946 | |
| 20 μL | |
| Primary | |
| Rat, Mouse, Human | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence, Western Blot | |
| 2F3B2 | |
| Unconjugated | |
| SEPT2 | |
| hNedd5, NEDD 5, NEDD5, SEPT2, SEPT2/septin 2, septin 2, septin2 | |
| Mouse | |
| Caprylic Acid Precipitation | |
| RUO | |
| 117515, 18000, 4735 | |
| -20°C | |
| Liquid |
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