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Invitrogen™ Sintilimab Recombinant Monoclonal Antibody
Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA559731
This item is not returnable.
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Description
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
Sintilimab is a fully human anti-PD-1 antibody for tumor immunotherapy. It adopts IgG4 molecular framework and modified its hinge region sequence (S228P). Sintilimab, as a programmed death receptor 1 (PD-1) blocker, can bind to PD-1 molecules on the surface of T cells and relieve the inhibitory effect of PD-1 pathway on T cells.
Specifications
| Sintilimab | |
| Recombinant Monoclonal | |
| Unconjugated | |
| IBI-308 | |
| Protein A | |
| RUO | |
| Human | |
| Antibody | |
| IgG4SP |
| ELISA, Flow Cytometry, Functional Assay, Surface Plasmon Resonance | |
| 1 mg/mL | |
| 25mM histidine with 8% sucrose, 0.01% Tween 80 and no preservative; pH 6.2 | |
| Human | |
| 100 μg | |
| Primary | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
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