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  8. Sivelestat sodium salt, Tocris Bioscience™

Sivelestat sodium salt, Tocris Bioscience™

Product Code. 18075692
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Selective leukocyte elastase inhibitor

Selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. Inhibits NF-κB activation and LTB4-induced neutrophil transmigration in vitro. Significantly attenuates ischemia-induced spinal cord injury, decreases serum cytokine levels and reduces acute inflammatory lung injury in vivo.

Chemical Identifiers

CAS 150374-95-1
Molecular Formula C20H21N2NaO7S
Molecular Weight (g/mol) 456.445
InChI Key ZAIFANJZUGNYCK-UHFFFAOYSA-M
Synonym sivelestat sodium, sivelestat sodium salt, unii-0cll4232kd, sivelestat sodium salt hydrate, ono-5046.na, sivelestat sodium anhydrous, sivelestatsodium, c20h21n2o7s.na, glycine, n-2-4-2,2-dimethyl-1-oxopropoxy phenyl sulfonyl amino benzoyl-, monosodium salt
PubChem CID 23664980
IUPAC Name sodium;2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetate
SMILES CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)[O-].[Na+]

Specifications

Quantity 50 mg
Formula Weight 456.44
Percent Purity >98%
Chemical Name or Material Sivelestat sodium salt
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