missing translation for 'onlineSavingsMsg'
Learn More
Learn More
SODD/BAG4 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 13913-1-AP-150UL
This item is not returnable.
View return policy
Description
This antibody detects 66-70 kDa full-length BAG4 protein and 45 kDa, 60 kDa C-terminal fragments.
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost.Specifications
| SODD/BAG4 | |
| Polyclonal | |
| Unconjugated | |
| BAG4 | |
| BAG 4, BAG4, Silencer of death domains, SODD | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 9530 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot | |
| 0.51 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| O95429 | |
| BAG4 | |
| SODD/BAG4 Fusion Protein Ag4905 | |
| 150 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction