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Invitrogen™ SR-BI Monoclonal Antibody (3D12)

Mouse Monoclonal Antibody
Brand: Invitrogen™ MA533380
Description
Product is supplied at 1 mL (100 μL/mL). Application Notes: Functional Assay- This antibody is useful for neutralization of the biological activity of SR-BI. For neutralization of biological activity dilutions have to be made according to the amounts SR-BI to be inactivated.
High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
Specifications
| SR-BI | |
| Monoclonal | |
| 100 μg/mL | |
| PBS with 0.1% BSA and no preservative | |
| P97943 | |
| SCARB1 | |
| Protein G | |
| RUO | |
| 25073 | |
| 4°C | |
| Liquid |
| Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen) | |
| 3D12 | |
| Unconjugated | |
| SCARB1 | |
| AI120173; CD36; CD36 and LIMPII analogous 1; CD36 antigen (collagen type I receptor thrombospondin receptor)-like 1 (scavanger receptor class B type 1); CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; CD36 antigen (collagen type I receptor, thrombospondin receptor-like 1); CD36 antigen-like 1; Cd36l1; CD36-related class B scavenger receptor haSR-BI; CLA1; Cla-1; Collagen type I receptor, thrombospondin receptor-like 1; D5Ertd460e; haSR-bI; HDL QTL 1; Hdlq1; HDLQTL6; high density lipoprotein receptor; Hlb398; mSR-BI; Scarb1; scavanger receptor class B type 1; scavenger receptor b1; scavenger receptor class B member 1; scavenger receptor class B type I; scavenger receptor class B type II; scavenger receptor class B type III; scavenger receptor class B, member 1; scavenger receptor class B1; SRB1; SR-B1; SRBI; SR-BI; SR-BII | |
| Mouse | |
| 100 μg | |
| Primary | |
| Rat | |
| Antibody | |
| IgG1 |
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