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  7. tert-Butyldimethylchlorosilane, 97%

tert-Butyldimethylchlorosilane, 97%

Code produit 11484364
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Code produit 11484364 Fournisseur Thermo Scientific Alfa Aesar Code fournisseur A13064.14
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Description

CAS: 18162-48-6 | C6H15ClSi | 150.721 g/mol

tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.

Solubility
Soluble in chloroform and ethyl acetate. Insoluble in water.

Notes
Moisture sensitive. Store in cool place. Incompatible with bases, metals, oxidizing agents and alcohols.
TRUSTED_SUSTAINABILITY

Identifiants chimiques

CAS 18162-48-6
Molecular Formula C6H15ClSi
Molecular Weight (g/mol) 150.721
MDL Number MFCD00000501
InChI Key BCNZYOJHNLTNEZ-UHFFFAOYSA-N
Synonym tert-butyldimethylsilyl chloride, tert-butyldimethylchlorosilane, t-butyldimethylchlorosilane, tert-butylchlorodimethylsilane, tbdms chloride, tert-butyl chloro dimethylsilane, chloro-tert-butyldimethylsilane, silane, chloro 1,1-dimethylethyl dimethyl, tbscl, t-butyldimethylsilyl chloride
PubChem CID 28928
ChEBI CHEBI:85071
IUPAC Name tert-butyl-chloro-dimethylsilane
SMILES CC(C)(C)[Si](C)(C)Cl

Spécification

Boiling Point 124°C to 126°C
Melting Point 86°C to 89°C
Quantity 25 g
Flash Point 22°C (72°F)
Odor Pungent
Sensitivity Moisture sensitive
Density 0.81
Linear Formula (CH3)3CSi(CH3)2Cl
UN Number UN2925
Beilstein 505999
Solubility Information Soluble in chloroform and ethyl acetate. Insoluble in water.
Formula Weight 150.73
Percent Purity 97%
Chemical Name or Material tert-Butyldimethylchlorosilane
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Sécurité et traitement

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Identifiant produit
  • tert-Butyldimethylchlorosilane
 Mention d'avertissement
  • Danger
 Catégorie de danger
  • LONG-TERM AQUATIC HAZARD Chronic 2
  • Serious eye damage/eye irritation Category 1
  • Flammable solid Category 2
  • Skin corrosion/irritation Category 1 A
 Mention de danger
  • H228-Flammable solid.
  • H314-Causes severe skin burns and eye damage.
  • H318-Causes serious eye damage.
  • H411-Toxic to aquatic life with long lasting effects.
 Conseils de prudence
  • P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310-Immediately call a POISON CENTER/doctor/.
 Informations supplémentaires
  • MIXTURE LIST-Contain: chloro(1,1-dimethylethyl)dimethyl-silane
FDS

RUO – Research Use Only

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