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TET3 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA534431
Additional Details : Weight : 0.01000kg
Description
A suggested positive control is SK-N-SH cell lysate. PA5-34431 can be used with blocking peptide PEP-1473.
TET3, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is most abundantly expressed in hematopoietic cells. Unlike the related TET2 protein, mutations in TET3 have not been observed in any myeloid malignancies. TET3 has been shown to be involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization and may also contribute to somatic cell nuclear reprogramming during animal cloning.Specifications
TET3 | |
Polyclonal | |
Unconjugated | |
TET3 | |
B430006D22Rik; BC037432; D230004J03Rik; hCG_40738; KIAA0401; Methylcytosine dioxygenase TET3; MGC22014; probable methylcytosine dioxygenase TET3; putative methylcytosine dioxygenase; Tet methylcytosine deoxygenase 3 isoform; tet methylcytosine dioxygenase 3; tet oncogene family member 3; Tet3 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
194388, 200424, 680576 | |
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
Liquid |
Immunohistochemistry, Western Blot | |
1 mg/mL | |
PBS with 0.02% sodium azide | |
O43151, Q8BG87 | |
TET3 | |
A 17 amino acid synthetic peptide near the carboxy terminus of human TET3 | |
100 μg | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |