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Thiazole, 99%

Product Code. 11322377
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Product Code. 11322377 Supplier Thermo Scientific Alfa Aesar Supplier No. L09970.03
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Description

CAS: 288-47-1 | C3H3NS | 85.12 g/mol

Thiazole is used as a flavoring agent and in the preparation of dyes and rubber accelerators. It serves as a component of the vitamin thiamine (B1). It acts as a protected formyl group used in natural product synthesis. It reacts with alkyl lithium and Grignard’s reagent to prepare organometallic complexes. It is involved in the electrophilic aromatic substitution and nucleophilic aromatic substitution at C-5 and C-2 positions respectively. Further, it undergoes alkylation reaction to get thiazolium cation, which is used as a catalyst in the Stetter reaction and the Benzoin condensation. In addition to this, it is involved in the preparation of alagebrium.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Thiazole is used as a flavoring agent and in the preparation of dyes and rubber accelerators. It serves as a component of the vitamin thiamine (B1). It acts as a protected formyl group used in natural product synthesis. It reacts with alkyl lithium and Grignard’s reagent to prepare organometallic complexes. It is involved in the electrophilic aromatic substitution and nucleophilic aromatic substitution at C-5 and C-2 positions respectively. Further, it undergoes alkylation reaction to get thiazolium cation, which is used as a catalyst in the Stetter reaction and the Benzoin condensation. In addition to this, it is involved in the preparation of alagebrium.

Solubility
Soluble in ethanol and ether. Slightly soluble in water.

Notes
Air and light sensitive. Incompatible with acids, acid chlorides, acid anhydrides, strong oxidizing agents and carbon dioxide.
TRUSTED_SUSTAINABILITY

Kemiska identifierare

CAS 288-47-1
Molecular Formula C3H3NS
Molecular Weight (g/mol) 85.12
MDL Number MFCD00005315
InChI Key FZWLAAWBMGSTSO-UHFFFAOYSA-N
Synonym thiazole, thiazol, unii-320rcw8pef, fema no. 3615, ccris 3205, 320rcw8pef, lom, racemic thiazole, 5h-thiazol-1-ium
PubChem CID 9256
ChEBI CHEBI:43732
IUPAC Name 1,3-thiazole
SMILES S1C=CN=C1

Specifikationer

Melting Point -33°C
Density 1.2
Boiling Point 117°C to 118°C
Flash Point 22°C (71°F)
Odor Unpleasant
Refractive Index 1.539
Quantity 1 g
UN Number UN1993
Beilstein 103852
Sensitivity Air and light sensitive
Merck Index 14,9307
Solubility Information Soluble in ethanol and ether. Slightly soluble in water.
Formula Weight 85.13
Percent Purity 99%
Chemical Name or Material Thiazole
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