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Invitrogen™ TRADD Recombinant Rabbit Monoclonal Antibody (24GB2230)
Rabbit Recombinant Monoclonal Antibody
146.00€ - 500.00€
Specifications
| Antigen | TRADD |
|---|---|
| Clone | 24GB2230 |
| Concentration | 0.8 mg/mL |
| Content And Storage | -20°C |
| Applications | Flow Cytometry, Western Blot, Immunocytochemistry |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
30276173
|
Invitrogen™
MA557287 |
100 μL |
500.00€
100µL |
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|
30274932
|
Invitrogen™
MA557288 |
20 μL |
146.00€
20µL |
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Description
TRADD Recombinant Monoclonal Antibody for Western Blot, ICC/IF, Flow
TRADD (Tumor necrosis factor receptor type 1-associated DEATH domain protein) is an important mediator of FAS and TNFR1 associated apoptotic signaling. The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12. TRADD acts by interacting with TRIP12 and leading to the disruption of the interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A. TRADD acts as an adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interation with FADD. Overexpression of TRADD leads to two major TNF-induced responses - apoptosis and activation of NF-kappa-B.Specifications
| TRADD | |
| 0.8 mg/mL | |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q15628, Q3U0V2 | |
| 246756, 71609, 8717 | |
| A synthesized peptide derived from human TRADD (aa 210-312). | |
| Antibody |
| 24GB2230 | |
| -20°C | |
| Recombinant Monoclonal | |
| Liquid | |
| IgG | |
| Human, Mouse, Rat | |
| TRADD | |
| 9130005N23Rik; AA930854; Hs.89862; Hs89862; MGC11078; TNF receptor 1 associated signal transducer; TNFR1-associated DEATH domain protein; TNFRSF1A associated via death domain; TNFRSF1A-associated via death domain; TRADD; tumor necrosis factor receptor type 1 associated death domain protein; tumor necrosis factor receptor type 1-associated DEATH domain protein; tumor necrosis factor receptor-1-associated protein | |
| TRADD | |
| Primary | |
| Affinity chromatography |
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