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TRK fused gene Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA565710
Additional Details : Weight : 0.01000kg
Description
Immunogen sequence: LRRELIELRNK VNRLLDSLEP PGEPGPSTNI PENDTVDGRE EKSASDSSGK QSTQVMAASM SAFDPLKNQD EINKNVMSAF GLTDDQVSGP PS Highest antigen sequence identity to the following orthologs - mouse 96%, rat 97%.
TFG protein, a recently identified novel protein, is a human homolog of mouse TFG protein. It contains an N-terminal coiled-coil structure, a SPYGQ-rich region followed by octicosapeptide repeats. Research shows that TFG can modulate SHP-1 activity and is a novel member of the NF-kB pathway. The physiological functions of this protein remain largely elusive, but TFG is thought to function by associating with other proteins, including TANK and NEMO. TFG was first identified as a partner of NTRK1 and is involved in generating the thyroid TRK-T3 oncogene, as well as oncogenic rearrangements with ALK in anaplastic lymphoma and NOR1 in mixoid chondrosarcoma.Specifications
TRK fused gene | |
Polyclonal | |
Unconjugated | |
TFG | |
AI173908; HMSNP; protein TFG; SPG57; TF6; TFG; Trk-fused gene; TRK-fused gene protein; TRKT3; TRKT3 oncogene | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
10342 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunocytochemistry, Western Blot | |
0.2 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q92734 | |
TFG | |
Recombinant Human TFG | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
For Research Use Only