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Tocris Bioscience™ Troglitazone
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Product Code. 18045712
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18045712 10 mg 10mg
18065202 50 mg 50mg
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Product Code. 18045712 Supplier Tocris Bioscience™ Supplier No. 3114/10

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Description

Selective PPARγ agonist; antidiabetic agent

Selective PPARγ receptor agonist (EC50 values are 780 and 555 nM at murine and human PPARγ receptors respectively). Displays no activity at PPARα or PPARδ receptors. Antidiabetic agent; exerts potent glucose-lowering effects in insulin-resistant diabetic mice. Displays anti-invasive effect on human breast cancer cells; reduces migration, adhesion and spreading on fibronectin-coated plates. Also inhibits cell growth of hematopoietic cell lines. Inhibits lamellipodia formation and actin polymerization.
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Chemical Identifiers

CAS 97322-87-7
Molecular Formula C24H27NO5S

Specifications

Quantity 10 mg
Formula Weight 441.54
Purity 98%
Molecular Weight (g/mol) 441.542
Chemical Name or Material Troglitazone
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