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TXNRD1 Monoclonal Antibody (OTI7B2), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA811366
This item is not returnable.
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Description
This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3′ UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.Specifications
| TXNRD1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| O89049, Q16881, Q9JMH6 | |
| Txnrd1 | |
| Full length human recombit protein of human TXNRD1 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Paraffin), Western Blot | |
| OTI7B2 | |
| Unconjugated | |
| TXNRD1 | |
| GRIM-12, TR, TR1, TRXR1, TXNR | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 50493, 58819, 7296 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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