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CD36 Antibody (185-1G2), DyLight 755, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-95271IR

Product Code. 18069876

  • 650.00€ / 0.10mL

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Description

Description

CD36 Monoclonal specifically detects CD36 in Human samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD36/SR-B3
Monoclonal
DyLight 755
CD36 antigen, CD36 molecule (thrombospondin receptor), FA6-152, FATCHDS7, Fatty acid translocase, Glycoprotein IIIb, GP3Bthrombospondin receptor), GPIIIB, Leukocyte differentiation antigen CD36, PAS IV, PAS-4, Platelet collagen receptor, platelet glycoprotein 4, Platelet glycoprotein IV, scavenger receptor class B, member 3, Thrombospondin receptor
Stimulated human leukocytes
0.1 mL
Cancer, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Immunology, Lipid and Metabolism, Stem Cell Markers
948
Human
Purified
Flow Cytometry, Immunofluorescence
185-1G2
50mM Sodium Borate
Mouse
Protein A or G purified
RUO
Primary
Recognizes a protein of 80kDa-90kDa, identified as CD36 (Workshop IV; Code P-26). Its epitope maps between aa155-183. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36. This monoclonal antibody blocks adhesion of P. falciparum parasitized red blood cells to CD36 and strongly inhibits collagen-induced platelet aggregation.
Store at 4°C in the dark.
IgG2a κ
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