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OCT2 Antibody (OCT2/2137), Alexa Fluor™ 350, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-75735AF350

Product Code. 18290628

  • 635.00€ / 0.10mL

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Description

Description

44471 Monoclonal specifically detects 44471 in Human samples. It is validated for Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

OCT2
Monoclonal
Alexa Fluor 350
50mM Sodium Borate with 0.05% Sodium Azide
POU2F2
Recombinant fragment of human OCT2 protein (around aa 112-297) (exact sequence is proprietary) (Uniprot: P09086)
0.1 mL
Cancer
OCT2 is a transcription factor of the POU homeo-domain family that binds to the Ig gene octamer sites, regulating B-cell-specific genes. OCT2 expression can be used as a marker of B-cell lineage and differentiation. Germinal center B-cells, mantle B-cells, monocytoid B-cells, and plasma cells show high level expression of OCT2. Additionally, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, plasmacytoma, Burkitt lymphoma, diffuse large cell lymphoma, diffuse large B-cell lymphoma, Hodgkin lymphoma display increased expression of OCT2. Several studies of OCT2 expression have shown a low level expression in pre-B, T-cell, myelomonocytic, and epithelial cell lines, whereas all mature B-cell lines have high levels of expression. In spite of scanty evidence for OCT2 expression in T cells, it is believed that this factor participates in transcriptional regulation during T-cell activation.
Store at 4°C in the dark.
Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)
Oct2/2137
Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin
homeobox protein, Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, OCT2Oct-2, Octamer-binding protein 2, Octamer-binding transcription factor 2, OTF-2, OTF2POU domain class 2, transcription factor 2, POU class 2 homeobox 2, POU domain, class 2, transcription factor 2
Mouse
Protein A or G purified
RUO
Primary
Human
IgG1 κ
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