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VPS34 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA146456

Additional Details : Weight : 0.01000kg

Product Code. 10018943

  • 462.00€ / 100µL
Estimated Shipment: 06-08-2024
to see stock.

Description

Description

The target sequence has 87% sequence homology with xenopus. Suggested positive control: HepG2 whole cell lysates, antigen standard for PIK3C3 (transient overexpression lysate).

PIK3C3 (hVPS34) is the sole class III member of the PI3 Kinase family. PIK3C3 phosphorylates phosphatidylinositol (PI) to produce phosphatidylinositol 3-phosphate [PI(3)P], which recruits downstream effectors containing FYVE and Phox domains to membranes. PIK3C3 is involved in coupling nutrient signaling to mTOR and also plays a role in autophagy and intracellular trafficking. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes.
Specifications

Specifications

VPS34
Polyclonal
Unconjugated
Pik3c3
5330434F23Rik; catalytic phosphatidylinositol 3-kinase 3; catalytic subunit type 3 Antibody; class 3 phosphoinositide-3-kinase; Class III PI 3-kinase; hVps34; hVps34 Antibody; OTTMUSP00000023341; OTTMUSP00000023350; phosphatidylinositol 3-kinase; Phosphatidylinositol 3-kinase catalytic subunit type 3; phosphatidylinositol 3-kinase p100 subunit; phosphatidylinositol 3-kinase, catalytic subunit type 3; Phosphoinositide-3-kinase class 3; phosphoinositide-3-kinase, class 3; PI3K type 3; PI-3K Vps34p; pi3kc3; PI3-kinase type 3; Pik3c3; PIK3C3 Antibody; PtdIns-3-kinase type 3; VPS34
Rabbit
Antigen affinity chromatography
RUO
225326, 503700, 5289, 65052
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunocytochemistry, Western Blot
0.2 mg/mL
PBS with 0.1% BSA, 50% glycerol and 0.05% sodium azide
O88763, Q5D891, Q6PF93, Q8NEB9
Pik3c3
Synthetic peptide made to an internal portion (within residues 700-850) of human VPS34.
100 μL
Primary
Human, Mouse, Porcine, Rat
Antibody
IgG
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