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  8. ZM 39923 hydrochloride, Tocris Bioscience™

ZM 39923 hydrochloride, Tocris Bioscience™
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Product Code. 18073912
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Product Code. 18073912 Supplier Tocris Bioscience Supplier No. 1367/10

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Description

Potent, selective JAK3 inhibitor

Potent, selective inhibitor of Janus tyrosine kinase 3 (JAK3). pIC50 values are 7.1, 5.6, 4.4, and < 5.0 for JAK3, EGFR, JAK1 and CDK4 respectively. Breaks down in neutral buffer (t½ = 36 mins, pH 7.43, 25°C) to form ZM 449829 (Cat. No. 1366).
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 58753-54-1
Molecular Formula C23H26ClNO
Molecular Weight (g/mol) 367.917
InChI Key NJTUORMLOPXPBY-UHFFFAOYSA-N
PubChem CID 176406
IUPAC Name 3-[benzyl(propan-2-yl)amino]-1-naphthalen-2-ylpropan-1-one;hydrochloride
SMILES CC(C)N(CCC(=O)C1=CC2=CC=CC=C2C=C1)CC3=CC=CC=C3.Cl

Specifications

Quantity 10 mg
Synonym zm 39923 hydrochloride, jak3 inhibitor iv, zm39923 hydrochloride, 3-benzyl isopropyl amino-1-naphthalen-2-yl propan-1-one hydrochloride, 3-benzylisopropylamino-1-naphthalen-2-yl-propan-1-one hydrochloride, 2-naphthyl-n-isopropyl,n-benzyl-beta-aminoethylketone, hci, 3-n-benzyl-n-isopropyl amino-1-naphthalen-2-yl propan-1-one hydrochloride, c23h25no.clh
Formula Weight 367.92
Percent Purity >99%
Chemical Name or Material ZM 39923 hydrochloride
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