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Invitrogen™ 14-3-3 beta Monoclonal Antibody (03)
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Product Code. 17188925
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
17188925 100 μL 100µL
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Product Code. 17188925 Supplier Invitrogen™ Supplier No. MA529647

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Description

Mouse Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human 14-3-3 beta/YWHAB.

14-3-3, a family of acidic and soluble proteins, highly conserved in amino acid sequences from yeast to mammals, is expressed in all eukaryotic cells. Seven isoforms(beta, gamma, epsilon, eta, zeta, sigma and tau/theta) encoded by seven distinct genes are identified in mammals and forms homo- and hetero- dimeric cup-shaped structures. As 14-3-3 is interacted with more than 100 binding partners, it regulates key proteins involved in various biological processes such as signal trans-duction, cell cycle, transcriptional control, cell proliferation, apoptosis, and ion channel physiology. Most 14-3-3 requires phosphorylation of serine or threonine residues in the target sequence. This protein is abundantly expressed in the brain and has been detected in the cerebrospinal fluid of patients with different neurological disorders.
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Specifications

Antigen 14-3-3 beta
Applications ELISA, Flow Cytometry, Immunocytochemistry
Classification Monoclonal
Clone 03
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene YWHAB
Gene Accession No. P31946
Gene Alias 1300003C17Rik; 14-3-3 alpha; 14-3-3 protein beta; 14-3-3 protein beta/alpha; 14-3-3 protein beta/alpha, N-terminally processed; 14-3-3 protein beta-subtype; 3-monooxygenase/tryptophan 5 monooxygenase activation protein beta polypeptide; brain protein 14-3-3, beta isoform; epididymis secretory protein Li 1; GW128; HEL-S-1; HS1; hypothetical protein GW128; KCIP 1; KCIP1; KCIP-1; Prepronerve growth factor RNH-1; protein 1054; Protein kinase C inhibitor protein 1; protein kinase C inhibitor protein-1; QccE-16215; RP1-148E22.1; tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta polypeptide; tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; tyrosine 3/tryptophan 5 -monooxygenase activation protein beta polypeptide; tyrosine 3/tryptophan 5 -monooxygenase activation protein, beta polypeptide; tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein beta polypeptide; tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein, beta polypeptide; tyrosine 3-monooxgenase/tryptophan 5-monooxgenase activation protein, beta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide; unnamed protein product; YWHAA; Ywhab
Gene Symbols YWHAB
Host Species Mouse
Immunogen Recombinant Human 14-3-3 beta/YWHAB protein (Met1-Asn246).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7529
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b
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