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γ-Catenin Mouse, Unlabeled, Clone: 15, BD
Mouse Monoclonal Antibody
178.69€ - 323.14€
Specifications
| Antigen | γ-Catenin |
|---|---|
| Clone | 15 |
| Concentration | 250μg/mL |
| Applications | Western Blot |
| Classification | Monoclonal |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15895359
|
BD Biosciences
610253 |
50 μg |
 179.00€ 178.69€ / 1 set Save 0.31€ 0.17% Off |
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|
15805369
|
BD Biosciences
610254 |
150 μg |
325.00€ 323.14€ / 1 set Save 1.86€ 0.57% Off |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
γ-Catenin (plakoglobin) was identified as a compenent of desmosomes where it associates with desmoglein. γ-Catenin and β-Catenin are closely related proteins that have significant homology with the Drosophila armadillo protein. In addition to complexing with E-Cadherin, γ-Catenin and β-Catenin have been observed in association with the intracellular domain of N-Cadherin. It has been proposed that one molecule of α-Catenin and at least one molecule of β-Catenin and γ-Catenin simultaneously bind to a single cadherin molecule. A 19 amino acid sequence of desmoglein (Dsg1) was found to be critical for binding of γ-Catenin. This region has significant homology to the catenin-binding domain of classical cadherins, thus suggesting a common mechanism for γ-Catenin localization at both adherens junctions and desmosomes.
Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting
Specifications
| γ-Catenin | |
| 250μg/mL | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| IgG2a | |
| Affinity Purified |
| 15 | |
| Western Blot | |
| Unconjugated | |
| RUO | |
| Canine, Chicken, Human, Mouse, Rat | |
| Human γ-Catenin aa. 553-738 | |
| Primary | |
| Store undiluted at -20°C. |
For Research Use Only.
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