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Tocris Bioscience™ BAY 41-2272
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Product Code. 18065322
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Product Code. 18065322 Supplier Tocris Bioscience™ Supplier No. 4430/10

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Description

Soluble guanylyl cyclase (sGC) activator

Activator of soluble guanylyl cyclase (sGC); acts at a nitric oxide (NO)-independent regulatory site in the sGC α1 subunit. Inhibits platelet aggregation (IC50 = 36 nM) and phenylephrine-induced contractions of rabbit aorta (IC50 = 0.30 μM). Also reduces vascular smooth muscle growth through cAMP- and cGMP-dependent PKA and PKG pathways.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 256376-24-6
Molecular Formula C20H17FN6

Specifications

Quantity 10 mg
Formula Weight 360.39
Purity >98%
Molecular Weight (g/mol) 360.40
Chemical Name or Material BAY 41-2272
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