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  6. Invitrogen™ BIN1 Recombinant Rabbit Monoclonal Antibody (K01_1N57)

Invitrogen™ BIN1 Recombinant Rabbit Monoclonal Antibody (K01_1N57)
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Product Code. 30829229
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30829229 100 μL
30826690 50 μL
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Product Code. 30829229 Supplier Invitrogen™ Supplier No. MA563272

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Description

Rabbit Recombinant Monoclonal Antibody

BIN1 Recombinant Monoclonal Antibody for Western Blot

This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BIN1
Applications Western Blot
Classification Recombinant Monoclonal
Clone K01_1N57
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 150mM NaCl, 40% glycerol, 0.05% BSA and 0.01% sodium azide; pH 7.4
Gene BIN1
Gene Accession No. O00499
Gene Alias ALP-1; AMPH 2; Amph2; amphiphysin 2; amphiphysin II; amphiphysin IIamph2; amphiphysin-like; amphiphysin-like protein; AMPHL; Bin1; box dependant MYC interacting protein 1; box-dependent myc-interacting protein 1; BRAMP-2; bridging integrator 1; DKFZp547F068; MGC10367; MGC105358; myc box dependent interacting protein 1; myc box-dependent-interacting protein 1; SH3 domain-containing protein 9; SH3P9; similar to bridging integrator 1 isoform 9
Gene Symbols BIN1
Host Species Rabbit
Immunogen Recombinant protein of human BIN1.
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 274
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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