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Invitrogen™ Calpain 12 Polyclonal Antibody

Description
Antibody detects endogenous levels of total CAPN12.
The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.
Specifications
Specifications
| Antigen | Calpain 12 |
| Applications | Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | CAPN12 |
| Gene Accession No. | Q6ZSI9, Q9ER56 |
| Gene Alias | calcium-activated neutral proteinase 12; calpain 12; calpain-12; CANP 12; CAPN12 |
| Gene Symbols | CAPN12 |
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