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  6. Casein Kinase 1 epsilon Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Casein Kinase 1 epsilon Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16878163 Shop All Proteintech Products
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20 μL
150 μL
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150µL
20µL
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16878163 20 μL 20µL
16868163 150 μL 150µL
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Product Code. 16878163 Supplier Proteintech Supplier No. 112301AP20UL

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Description

Rabbit Polyclonal Antibody

Casein kinases are a group of ubiquitous Ser/Thr kinases that phosphorylate key regulatory proteins involved in the control of cell differentiation, proliferation, chromosome segregation, circadian rhythms, and metabolic pathways. CK1 family members share a highly conserved kinase domain but differ in their variable N-and C-terminal domains. Mammals have seven family members: alpha, beta, gamma1, gamma2, gamma3, delta and epsilon. They all share at least 50% amino acid identity within the protein kinase catalytic domain. CK1 isoforms exclusively use ATP as phosphate donor and are generally co-factor independent. Casein kinase I epsilon is a Wnt-regulated kinase, and regulated phosphorylation of Dvl allows fine tuning of the Wnt-b-catenin signaling pathway. CKIe positively regulates Akt possibly by inhibiting PP2A. CKIe play an important role in neurodegenerative diseases.

Specifications

Antigen Casein Kinase 1 epsilon
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene CSNK1E
Gene Accession No. P49674, Q9JMK2
Gene Alias Casein Kinase 1 epsilon, casein kinase 1, epsilon, CKI epsilon, CKIe, CSNK1E, HCKIE
Gene Symbols CSNK1E
Host Species Rabbit
Immunogen Casein Kinase 1 epsilon Fusion Protein Ag1742
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1454, 27373, 58822
Target Species Human, Rat, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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