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CBX4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00€ - 410.00€

Specifications

Antigen CBX4
Concentration 0.27 mg/mL
Applications Immunocytochemistry, Western Blot, Immunofluorescence
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16878534
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Proteintech
18544-1-AP-20UL
20 μL
145.00€
20µL
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16868534
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Proteintech
18544-1-AP-150UL
150 μL
410.00€
150µL
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Description

Description

Polycomb group (PcG) proteins are chromatin-associated proteins which are important for embryonic and adult stem cell self-renewal and maintece. At least two distinct human PcG complexes have been identified. Polycomb repressive complex I (PRC1) contains CBX4/Pc2, HPH1 and RING domain-containing proteins (RING1, RING2 and BMI1). CBX4 (Chromobox protein homolog 4 or PC2), which functions as a transcriptional suppressor, is a candidate of KyoT2-binding proteins. It is a E3 SUMO-protein ligase which facilitates SUMO1 conjugation. Depletion of CBX4 results in decreased cellular resistance to ionizing radiation. CBX4 is directly involved in the cellular response to DNA damage.
Specifications

Specifications

CBX4
Immunocytochemistry, Western Blot, Immunofluorescence
Unconjugated
Rabbit
Human, Mouse, Rat
O00257, O55187
12418, 501403, 8535
CBX4 Fusion Protein Ag13425
Primary
-20°C
CBX4
0.27 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
CBX4, Chromobox protein homolog 4, E3 SUMO protein ligase CBX4, hPC2, NBP16, PC2, Polycomb 2 homolog
Cbx4
IgG
Antigen Affinity Chromatography
Antibody
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Documents

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