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CD150 (SLAM) Hamster, anti-Mouse, PE-Cyanine7, Clone: TC15-12F12.2, STEMCELL Technologies

Hamster Monoclonal Antibody

284.85€ - 785.70€

Specifications

Antigen CD150 (SLAM)
Clone TC15-12F12.2
Applications Immunohistochemistry, Flow Cytometry, Immunofluorescence, Functional Assay, Immunoprecipitation
Classification Monoclonal
Conjugate PE-Cyanine7
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17188681
Encompass_Preferred
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Stemcell Technologies
60036CZ.1
25 μg
284.85€
25µg
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17178681
Encompass_Preferred
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Stemcell Technologies
60036CZ
100 μg
785.70€
100µg
View alternative products
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Description

Description

  • The TC15-12F12
  • 2 antibody reacts with CD150 (signaling lymphocyte activation molecule or SLAM), an ∼75 kDa type I transmembrane glycoprotein that plays multiple roles in the immune response by serving as a cell adhesion molecule and/or coreceptor
  • It is differentially expressed by T cells, immature thymocytes, B cells, dendritic cells, macrophages, and endothelial cells
  • The expression pattern differs according to cell type and activation status
  • Expression is rapidly induced upon activation of T cells, B cells and dendritic cells, with synthesis by T cells being maintained on Th1 but not Th2 clones
  • CD150-mediated co-stimulation of TCR-activated T cells enhances the production of IFN-γ by Th1 cells, a response that can be augmented by binding of the TC15-12F12
  • 2 antibody
  • CD150 is thought to mediate signal transduction by associating with the intracellular protein tyrosine phosphatase, SHP-2
Specifications

Specifications

CD150 (SLAM)
Immunohistochemistry, Flow Cytometry, Immunofluorescence, Functional Assay, Immunoprecipitation
PE-Cyanine7
Mouse
Primary
TC15-12F12.2
Monoclonal
Hamster
IgG2a λ
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