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  6. CD45 Mouse, anti-Human, FITC, Clone: 2D1, STEMCELL Technologies

CD45 Mouse, anti-Human, FITC, Clone: 2D1, STEMCELL Technologies

Mouse Monoclonal Antibody

311.85€ - 685.80€

Specifications

Antigen CD45
Clone 2D1
Applications Flow Cytometry
Classification Monoclonal
Conjugate FITC
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17169151
Encompass_Preferred
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Stemcell Technologies
60123FI.1 		25 Tests
311.85€
25 tests
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17159151
Encompass_Preferred
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Stemcell Technologies
60123FI 		100 Tests
685.80€
100 tests
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Description

Description

  • The 2D1 antibody reacts with all isoforms of CD45, a type I transmembrane glycoprotein expressed on the surface of hematopoietic stem and progenitor cells and mature blood cells, except mature erythrocytes, platelets, and plasma cells; expression of CD45 is lost during differentiation of these cell lineages
  • CD45 is a member of the protein tyrosine phosphatase family and functions in a number of immunoregulatory processes, including cell activation, growth, differentiation, and oncogenic transformation
  • The large cytoplasmic portion of CD45 contains two tyrosine phosphatase domains, one of which is enzymatically active, that are involved in modulating the function of intracellular substrates such as the Src kinases Lck and Fyn
  • Alternative splicing of three exons (4, 5, and 6) encoding the extracellular RA, RB, and RC polypeptide sequences gives rise to up to 8 isoforms with molecular masses in the range of 180 - 240 kDa
Specifications

Specifications

CD45
Flow Cytometry
FITC
Human
Primary
2D1
Monoclonal
Mouse
IgG1 κ
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