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Invitrogen™ CD53 Polyclonal Antibody
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Código de producto. 16546071
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Quantity:
100 μL
Tamaño de la unidad:
100µL
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16546071 100 μL 100µL
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Código de producto. 16546071 Proveedor Invitrogen™ N.º de proveedor PA587622

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Descripción

Rabbit Polyclonal Antibody

Immunogen sequence: AILLFVYEQK LNEYVAKGLT DSIHRYHSDN STKAAWDSIQ SFLQCCGING TSDWTSGPPA SCPSDRKVEG CYAKARLWFH S; Positive Samples: B cells, Jurkat, Raji, HL-60, Mouse liver, Mouse spleen, Mouse lung; Cellular Location: Cell junction, Cell membrane, Membrane, Multi-pass membrane protein.

CD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage. This molecule has been reported to form complexes with other leukocyte surface proteins such as CD2, CD19, CD21, MHC II, VLA-4 or tetraspanins CD37, CD81 and CD82, thus probably modulating various signaling processes. CD53 is involved in radioresistancy of tumor cells and its triggering has anti-apoptotic effect. In thymus, CD53 is up-regulated in response to positive selection signals during T cell development, and is strongly expressed upon macrophage exposure to bacterial lipopolysaccharide, whereas stimulation of neutrophils results in down-regulation of CD53 expression.
TRUSTED_SUSTAINABILITY

Especificaciones

Antigen CD53
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.09 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Cd53
Gene Accession No. P19397, Q61451
Gene Alias AI323659; antigen MOX44 identified by monoclonal antibody MRC-OX44; Cd53; CD53 antigen; CD53 glycoprotein; CD53 molecule; CD53 tetraspan antigen; cell surface antigen; cell surface glycoprotein CD53; Leukocyte antigen MRC OX-44; leukocyte surface antigen CD53; MOX44; OX44; Ox-44; tetraspanin-25; transmembrane glycoprotein; TSPAN25; tspan-25
Gene Symbols Cd53
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 100-180 of human CD53 (NP_0005511).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12508, 963
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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