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Invitrogen™ CDH10 Polyclonal Antibody

Description
Immunogen sequence: CSPEIMFRRT PVPQQRILSS RVPRSDGKIL HRQKRGWMWN QFFLLEEYTG SDYQYVGKLH SDQDKGDGSL KYILSGDGAG TLFIIDEKTG DIHATRRIDR EEKAFYTLRA QAINRRTLRP VEPESEFVIK IHDINDNEPT FPEEIYTASV PEMSVVGTSV VQVTATDADD PSYGNSARVI YSILQGQPYF SVEPETGIIR TALPNMNREN REQYQVVIQA KDMGGQMGGL SGTTTVNITL T.
CDH10 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance.
Specifications
Specifications
| Antigen | CDH10 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Concentration | 0.63 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | Cdh10 |
| Gene Accession No. | P70408, Q9Y6N8 |
| Gene Alias | A830016G23Rik; C030003B10Rik; C030011H18Rik; Cadherin; cadherin 10; cadherin 10 type 2; cadherin 10, type 2 (T2-cadherin); cadherin-10; Cdh10; T2-cadherin |
| Gene Symbols | Cdh10 |
| Show More |
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