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Description
This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.
Specifications
Specifications
| Antigen | COSMC |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | C1GALT1C1 |
| Gene Accession No. | Q499P3, Q96EU7, Q9JMG2 |
| Gene Alias | C1Gal T2, C1GALT1 chaperone 1, C1GALT1 specific chaperone 1, C1GALT1C1, C1GALT2, c38h2 l1, C38H2 like protein 1, Core 1 beta3 Gal T2, COSMC, HSPC067, MSTP143, UNQ273/PRO310 |
| Gene Symbols | C1galt1c1 |
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