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Invitrogen™ CRSP130 Polyclonal Antibody

Product Code. 16556121
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Quantity:
100 μL
Unit Size:
100µL
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16556121 100 μL 100µL
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Product Code. 16556121 Supplier Invitrogen™ Supplier No. PA587691

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LLKPNDFRNR VSDFVKENSP EHWLQNDWHT KHMNYHKKYP EKLYFEGLAE QVDPPVQIQS PYLPIYFGNV CLRFLPVFDI VIHRFLELLP VSKSLETLLD HLGGLYKFHD RPVTYLYNTL HYYEMHLRDR AFLKRKLVHA IIGSLKDNRP QGWCLSDTYL KCAMNAREEN PWVPDDTYYC RLIGRLVDTM AGKSPGPFPN CDWRFNEFPN PAAHALHVTC V; Positive Samples: Mouse brain, Rat brain; Cellular Location: Nucleus.

CRSP is ubiquitously expressed in various tissues and functions as a multimeric complex that consists of nine distinct subunits. Several members of the CRSP family share sequence similarity with multiple components of the yeast transcriptional mediator proteins, including CRSP150, which is related to yeast Rgr1, and CRSP70, which is similar to the elongation factor TFIIS. CRSP77 and CRSP150 are also related to proteins within the putative murine mediator complex, while CRSP130 and CRSP34 are largely unrelated to either murine or yeast proteins. CRSP subunits also associate with larger multimeric co-activator complexes, including ARC/DRI, which binds directly to SREBP and nuclear hormone receptors to facilitate transcription, and with NAT, a polymerase II-interacting complex that represses activated transcription.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CRSP130
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 3.76 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MED23
Gene Accession No. Q5EB59, Q80YQ2, Q9ULK4
Gene Alias 130 kDa transcriptional co-activator; 130kDa; 133 kDa transcriptional co-activator; 3000002A17Rik; activator-recruited cofactor 130 kDa component; ARC130; Cofactor required for Sp1 transcriptional activation subunit 3; cofactor required for Sp1 transcriptional activation, subunit 3 (130kD); CRSP complex subunit 3; CRSP130; CRSP133; Crsp3; DRIP130; ESTM7; hSur-2; KIAA1216; Med23; Mediator complex subunit 23; mediator complex subunit MED23 variant MED23_i6; mediator complex subunit MED23 variant MED23_i7; mediator of RNA polymerase II transcription subunit 23; mKIAA1216; MRT18; mSur-2; Protein sur-2 homolog; SUR2; SUR-2; Transcriptional coactivator CRSP130; vitamin D3 receptor interacting protein; Vitamin D3 receptor-interacting protein complex 130 kDa component; X83317
Gene Symbols MED23
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 890-1110 of human MED23 (NP_0012574501).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 309565, 70208, 9439
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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