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Invitrogen™ CYP1A2 Monoclonal Antibody (3B8C1)
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Product Code. 11535752
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Quantity:
100 μL
Unit Size:
100µL
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11535752 100 μL 100µL
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Product Code. 11535752 Supplier Invitrogen™ Supplier No. MA3037

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Description

Mouse Monoclonal Antibody

MA3-037 detects Cytochrome P450 1A2 from human and non-human primate samples. MA3-037 has been successfully used in Western blot, immunocytochemistry and immunofluorescence applications. By Western blot, this antibody detects a ~58 kDa band representing Cytochrome P450 1A2. The MA3-037 immunogen is rat cytochrome P450 protein.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP1A2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 3B8C1
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.05% sodium azide
Gene Cyp1a2
Gene Accession No. P04799, P05177
Gene Alias aromatic compound inducible; aryl hydrocarbon hydroxylase; cholesterol 25-hydroxylase; CP12; CYP; Cyp1a1; Cyp1a2; Cyp1a-2; CYPD45; CYPIA2; Cytochrome P(3)450; cytochrome P-448; cytochrome P450 1A2; Cytochrome P450 4; cytochrome P450 family 1 subfamily A member 2; cytochrome P450 family 1 subfamily a polypeptide 1; Cytochrome P450 subfamily I (aromatic compound-inducible) member A2 (Q42 form d); cytochrome P450, 1a2; cytochrome P450, 1a2, aromatic compound inducible; cytochrome P450, family 1, subfamily A, polypeptide 2; cytochrome P450, subfamily I (aromatic compound-inducible), member A2 (Q42, form d); cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2; Cytochrome P-450d; cytochrome P450-D; Cytochrome P450-P2; cytochrome P450-P3; dioxin-inducible P3-450; flavoprotein-linked monooxygenase; Hydroperoxy icosatetraenoate dehydratase; microsomal monooxygenase; P(3)450; P3-450; P-448; P450; P450 4; P450 form 4; P450(PA); P450-3; P-450d; P450-D; P450-P3; RATCYPD45; xenobiotic monooxygenase
Gene Symbols Cyp1a2
Host Species Mouse
Immunogen Rat cytochrome P450 protein.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1544, 24297
Target Species Human, Monkey, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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