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Invitrogen™ DGCR2 Polyclonal Antibody

Description
Immunogen sequence: IHPDSVFYDPA DDDAFEPVEV SLPAPGDGGS EGALLRRLEQ PLPTAGASLA DLEDSADSSS ALLVPPDPAQ SGSTPAAEAL PGGGRHSRSS LNTV Highest antigen sequence identity to the following orthologs - mouse 83%, rat 82%.
Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome.
Specifications
Specifications
| Antigen | DGCR2 |
| Applications | Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.05 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | DGCR2 |
| Gene Accession No. | P98153 |
| Gene Alias | 9930034O06Rik; Dgcr2; Dgsc; DGS-C; DiGeorge syndrome critical region gene 2; DiGeorge syndrome critical region protein 2; DiGeorge syndrome gene c; DiGeorge syndrome protein C; IDD; integral membrane protein deleted in DiGeorge syndrome; integral membrane protein DGCR2/IDD; KIAA0163; Lan; mKIAA0163; seizure-related membrane-bound adhesion protein; Sez12; Sez-12 |
| Gene Symbols | DGCR2 |
| Show More |
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