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Invitrogen™ DOT5 Polyclonal Antibody

Description
DOT5 Polyclonal Antibody for Western Blot, ELISA
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Has a role in telomere silencing, which is the repression of chromatin structure which leads to a stop in the transcription of nearby genes. Also has a role in the regulation of telomere length. Acts as an alkyl-hydroperoxide reductase in the nucleus during post-diauxic growth. Preferentially reduces alkyl-hydroperoxides rather than hydrogen peroxide. Acts as an antioxidant necessary for stationary phase survival.
Specifications
Specifications
| Antigen | DOT5 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Concentration | 3.9 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4 |
| Gene | DOT5 |
| Gene Accession No. | P40553 |
| Gene Alias | Peroxiredoxin DOT5 DOT5 YIL010W |
| Gene Symbols | DOT5 |
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