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Invitrogen™ Doublecortin Monoclonal Antibody (3E1)

Product Code. 17885097
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500 μL
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500µL
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Product Code. Quantity unitSize
17885097 500 μL 500µL
17895267 100 μL 100µL
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Product Code. 17885097 Supplier Invitrogen™ Supplier No. MA547314

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Description

Mouse Monoclonal Antibody

Doublecortin Monoclonal Antibody for Western Blot, ICC/IF, IHC

In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. It contains two doublecortin domains, which bind microtubules. In addition, this protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in the gene encoding DCX are a cause of X-linked lissencephaly.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Doublecortin
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 3E1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 5mM sodium azide
Gene DCX
Gene Accession No. O43602, O88809, Q9ESI7
Gene Alias DBCN; Dbct; DC; Dcn; DCX; doublecortex; doublecortin; doublin; lissencephalin-X; lissencephaly, X-linked (doublecortin); LISX; Lis-X; LIS-XD; Neuronal migration protein doublecortin; OTTHUMP00000023860; OTTHUMP00000216316; SCLH; XLIS
Gene Symbols DCX
Host Species Mouse
Immunogen Recombinant full length human Lis-A isoform of doublecortin expressed in and purified from E. coli.
Purification Method Purified
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13193, 1641, 84394
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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