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Invitrogen™ DR4 Recombinant Rabbit Monoclonal Antibody (001), HRP

Description
DR4 Recombinant Monoclonal Antibody for ELISA
TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).
Specifications
Specifications
| Antigen | DR4 |
| Applications | ELISA |
| Classification | Recombinant Monoclonal |
| Clone | 001 |
| Concentration | 100 μg/mL |
| Conjugate | HRP |
| Formulation | PBS with no preservative |
| Gene | TNFRSF10A |
| Gene Accession No. | O00220 |
| Gene Alias | APO2; CD261; cytotoxic TRAIL receptor; death receptor 4; DR4; MGC9365; sCD261; soluble CD261; soluble TRAIL; sTRAIL; TNF receptor superfamily member 10a; TNF-related apoptosis-inducing ligand receptor 1; TNFRSF10A; TRAIL R1; TRAIL receptor 1; TRAILR1; TRAIL-R1; TRAILR-1; tumor necrosis factor receptor superfamily member 10A; tumor necrosis factor receptor superfamily member 10a variant 2; tumor necrosis factor receptor superfamily, member 10a |
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