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DR6 Mouse anti-Human, Clone: 3C2D10, Proteintech

Mouse Monoclonal Antibody

145.00€ - 410.00€

Specifications

Antigen DR6
Clone 3C2D10
Concentration 1 mg/mL
Applications Western Blot
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16808925
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Proteintech
66754-1-IG-20UL
20 μL
145.00€
20µL
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16898915
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Proteintech
66754-1-IG-150UL
150 μL
410.00€
150µL
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Description

Description

DR6 is widely expressed in human tissues and cell lines. The ligand for DR6 has not been identified. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor-6. Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kappa-B and JNK.
Specifications

Specifications

DR6
1 mg/mL
Monoclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
BM 018, CD358, Death receptor 6, DR6, TNFRSF21
TNFRSF21
IgG1
Protein G
Antibody
3C2D10
Western Blot
Unconjugated
Mouse
Human
O75509
27242
DR6 Fusion Protein Ag14327
Primary
-20°C
TNFRSF21
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Documents

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