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Invitrogen™ EDG2 Polyclonal Antibody
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Product Code. 11595882
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Quantity:
100 μg
Unit Size:
100µg
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11595882 100 μg 100µg
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Product Code. 11595882 Supplier Invitrogen™ Supplier No. PA11041

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Description

Rabbit Polyclonal Antibody

PA1-1041 detects lysophosphatidic acid receptor 1 protein in rat, human, mouse, and Xenopus samples. PA1-1041 has successfully been used in Western blot procedures. By Western blot, this antibody detects an ~42 kDa protein representing lysophosphatidic acid receptor 1 in PC12 and HeLa whole cell lysates as well as mouse and Xenopus liver samples. The PA1-1041 immunogen is a synthetic peptide corresponding to residues L(348) N H T I L A G V H S N D H S V V(364) of human LPA1. The immunizing sequence is completely conserved in human, mouse, rat and bovine. This peptide (Cat. # PEP-233) is available for use in neutralization and control experiments.

EDG2 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EDG2
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1 mg/mL BSA and 0.05% sodium azide
Gene LPAR1
Gene Accession No. P61793, P61794, Q92633
Gene Alias AI326300; Edg2; edg-2; endothelial differentiation lysophosphatidic acid G-protein-coupled receptor 2; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2; Gpcr26; Gpcr91; GPR26; G-protein coupled receptor 26; Kdt2; LPA receptor 1; LPA1; LPA-1; LPAR1; Lysophosphatidic acid receptor 1; lysophosphatidic acid receptor Edg-2; Mrec1.3; rec.1.3; rec1.3; ventricular zone gene 1; Vzg1; vzg-1
Gene Symbols LPAR1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues L(348) N H T I L A G V H S N D H S V V(364) of human LPA1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116744, 14745, 1902
Target Species Human, Mouse, Rat, Frog
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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