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FIG4 Polyclonal Antibody, Invitrogen™
Description
Immunogen sequence: VKEREKRKHER ILSEELVAAV TYLNQFLPPE HTIVYIPWDM AKYTKSKLCN VLDRLNVIAE SVVKKTGFFV NRPDSYCSIL RPDEKWNELG GCVIPTGR Highest antigen sequence identity to the following orthologs - mouse 99%, rat 97%.
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). In vitro, hydrolyzes all three D5-phosphorylated polyphosphoinositide substrates in the order PtdIns(4,5)P2 > PtdIns(3,5)P2 > PtdIns(3,4,5)P3. Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.
Specifications
Specifications
| Antigen | FIG4 |
| Applications | Immunocytochemistry, Immunofluorescence, Western Blot |
| Classification | Polyclonal |
| Concentration | 0.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | FIG4 |
| Gene Accession No. | Q92562 |
| Gene Alias | RP1-249I4.1; ALS11; CMT4J; KIAA0274; SAC3; dJ249I4.1; FIG4 homolog; SAC domain containing lipid phosphatase; FIG4 homolog; SAC1 domain containing lipid phosphatase; SAC domain-containing protein 3; Sac domain-containing inositol phosphatase 3; phosphatidylinositol 3; 5-bisphosphate 5-phosphatase; polyphosphoinositide phosphatase |
| Gene Symbols | FIG4 |
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For Research Use Only
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