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Invitrogen™ FOXB1/FOXB2 Polyclonal Antibody
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Product Code. 16667724
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Quantity:
100 μL
Unit Size:
100µL
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16667724 100 μL 100µL
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Product Code. 16667724 Supplier Invitrogen™ Supplier No. PA5101247

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total FOXB1/2.

The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FOXB1/FOXB2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene FOXB2
Gene Accession No. Q5VYV0, Q64732, Q64733, Q99853
Gene Alias bA159H20.4; C43; Fkh4; Fkh5; forkhead box B1; forkhead box B1a; forkhead box B1b; forkhead box B2; forkhead box protein B1; Forkhead box protein B2; forkhead homolog 4; Foxb1; Foxb1a; Foxb1b; FOXB2; Hfh-e5.1; HFKH-5; mesoderm/mesenchyme forkhead 3; Mf3; Transcription factor FKH-4; transcription factor FKH-5; Twh
Gene Symbols FOXB1, FOXB2
Host Species Rabbit
Immunogen A synthesized peptide derived from human FOXB1(Accession Q99853), corresponding to amino acid residues P293-H325.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14240, 27023, 442425, 64290
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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